In order to testify the theory of "Two Fever Peaks", he took a venture of self-infection trial. He said:" In case anything unexpected happens, please present me a circular wreath."

In the hot summer of 1981, A special patient was sent into the Affiliated Hospital Of GuangZhou College of TCM, who refused to take medicine with a hyperpyrexia of 40C.

The patient is called LiGuoqiao, who is the subdecanal, associate professor and the director of Research Lab of malaria. He was suffering from the disease of P.falciparum. This kind of disease is caused by the P.falcipraum plasmodia and it does a severe harm to human body. If the patient is not treated in time, the disease will further develop to cerebral malaria and cause death.

The day before yesterday, LiGuoqiao just came from the mountain area Monkey Ridge, Dongfang County,Hainan island where there live Li minority. The Malaria Research Base was located there. Long ago scientists set up a theory: "There is only a fever peak during the growth period of P.falciparum fissiparity."That was to say, patients only had one hyperpyrexia. However LiGuoqiao and his colleagues found there were two fever peaks in a period. Should it be testified, it would contribute a lot to the world.

The most convictive test is to conduct the infection trial on the healthy. Five days ago, LiGuoqiao asked his colleague to inject the blood of a P.falciparum patient into his body. Then, the first fever peak appeared. Fierce P.falciparum plasmodia was reproducing in a large quantity within his body and damaging his viscera such as liver, spleen, lung and cerebra capillary vessels. He was suffering from the hyperpyrexia with syndromes of vomiting, nausea and serious headache, and if it went on he would fell in a coma.

Guoxingbo, the vice-director of Research Lab of Malaria, said in tears:"Lao Li, I can't endure it anymore, please accept the medication!" As everybody knows, the medicine is very useful and effective, which is called Artemisinin (Qinghaosu) with high efficacy, quick acting and safety invented jointly by the Research Academe Of TCM etc.. It is better than another antimalarial-------chloroquine and it is the treasure of antimalarials. However, LiGuoqiao knew that as soon as he accepted the medicine, the P.falciparum plasmodia would be diminished. But he said to Guoxingbo:" No! We can't change our plan!" He asked for the paper and pen and wrote:" Even if in a coma, I will also refuse to accept the medication. This is totally the willing of my own and I asked Guoxingbo to help me do that. It is necessary for our research plan, so please don't blame him."

He said:" In case anything unexpected happens, please present me a circular wreath." The plasmodium is in the circular shape. The trial was continuing for four days and nights and at last the important discovery was testified by him.

For eighteen years, most of his time was spent in Hainan island, and he was called" Hainaness " by his wife.

LiGuoqiao was engaged in the clinical research and treatment of malaria in 1967. It was one of the national important scientific research projects.

After LiGuoqiao accepted the work task, he left his pregnant wife for Hainan island. Most of his time after that was spent in Hainan thus his wife called him" the Hainaness". He was so busy that he always worked for more than ten hours everyday with few of vacation. He promised to his daughters for thousand times that he would take them out to play, to visit Qixing Rock in ZhaoQing city. However, it was an empty cheque all the time.

In order to finish the task and also to conquer the malaria, he left the housework to his wife. In the past eighteen years, the family encountered many difficulties. As there were only females in family, they couldn't do the taskwork so they lived a tough life. He knew all of these, but he couldn't take a part of that.

LiGuoqiao also missed and cared his family. When his wife joined the Party, he was delighted and wrote to his wife for congratulation. When his daughters were in the school, he wrote to encourage them and asked them for pardon:"Dad is busy, so you should be self-disciplined and work hard." In the end of year, he took ginsengs home for his mother-in-law. When he would leave home again, he usually didn't forget to buy some bread, meat, and cooking oil, salt etc. for his family. He could only do that to fulfill the duty as a husband, a father and a son-in-law.

He climbed hills and mountains for outpatient; the most distance cost him three days on foot to go there.

In 1971, LiGuoqiao who was in Hainan heard of that malaria was epidemic in Yunnan boundary, and then he led a group to go there. They climbed hills and mountains, crossed villages and hamlets to investigate the epidemic situation and promote the medicine knowledge. Also they took the preventive and curative combined measures to decrease the morbidity of malaria there.

In a late evening, they got an information saying a cerebra malaria patient was in a serious coma from Awa mountain. He took up a medicine-chest and started out for there immediately with one of his colleagues. They started out at 5:00 in the morning and got the destination at 9:00 with the continuous climb of 12 hours. Although they were suffering from the hunger and fatigue, they still immediately started the salvage and finally saved the patient.

Where there was malaria patient, where there were they. Thus LiGuoqiao has worked in Yunnan boundary and Hainan island for eighteen years till now. In the eighteen years, he ate dried turnip, pickles and lobster sauce, lived in the shabby wooden hut. He couldn't remember how many times he went out for patients and how many hills and mountains he climbed. He only remembered the most distance cost him three days on foot continuously to go there. The working and living condition wasn't improved until 1981. In 1984, they founded the Research Lab of Malaria in Dongfang area, Dongfang county, Hainan island, and thus they had their" home" there.

In the eighteen years, LiGuoqiao and his colleagues got the prominent achievement. The mortality of cerebra malaria patient treated by them was the lowest in the world. That was an honor of Chinese!

In June, 1985, a patient in deep coma was sent into Dongfang area hospital.The patient was a lying-in woman who got the P.falciparum malaria, and the disease had developed to cerebra malaria. Several hours ago she had an abortion.

LiGuoqiao hurried to the hospital and examined the patient carefully, and found she had cerebra edema, heart failure, renal failure and hemolysis etc. syndromes. LiGuoqiao did his best to salvage the patient and tended the patient with Guoxingbo in turn. In order to avoid bedsores, they kept turning over the patient everyday. As the patient just had the abortion, she had the incontinent urine and stool and it was very smelly. But they weren't scared and kept cleaning the excretions. After totally seven days and nights, they managed to save the patient.

LiGuoqiao and his partners pulled the patients back from Azrael thus time after time. The mortality of cerebra malaria is 17% abroad while that treated by LiGuoqiao and his partners is 10% below. This is listed in the first class over the world and it is the honor of Chinese!

In the National Scientific Congress , 1978,the project of antimalarial artemisinin research under the cooperation with Chinese Research Institute etc. was granted the National Significant Scientific & Technology Fruit Award. In 1979, the project was granted the National Secondary Invention Award. In August, 1982 and December, 1984, the famous English medical magazine "Lance" published their thesis "The Antimalarial Fuction of Mefloquine And Artemisinin" and "Compatibility And Comparison of Mefloquine, Artemisinin and SP" in the front page and first item. In July, 1984, one of their theses was read in the Exchange Committee of Chinese Medicine and Pharmaceutical of Pacific area of American Scientific Promotion Committee which was held in the USA. In September of the same year, LiGuoqiao attended the Eleventh International Tropical Disease Malaria Committee upon the invitation. Three theses of them were read in the committee which attracted people's focus and was regarded by the present experts.

Recently, LiGuoqiao was granted as the Excellent Commie of GuangDong Universities in 1985. In the universities, research units and government of GuangDong area, LiGuoqiao's spirit was spread broadly.